Vhf05923 details

Gene vhfRNAi AccessionVhf05923
Gene SymbolSYT7
Gene DescriptionSynaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII)
Gene Name in PaperSYT7
GroupHost Factor
Ensembl Gene IDENST00000263846 ENST00000535826 ENST00000539008 ENST00000540677 ENST00000542670 ENST00000542836 
UniProt IDO43581
Entrez Gene ID9066
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)