Vhf05916 details

Gene vhfRNAi AccessionVhf05916
Gene SymbolMICB
Gene DescriptionMHC class I polypeptide-related sequence B (MIC-B)
Gene Name in PaperMICB
GroupHost Factor
Ensembl Gene IDENST00000399150 ENST00000427115 ENST00000428416 ENST00000436531 ENST00000436655 ENST00000438954 ENST00000443156 ENST00000546706 ENST00000551608 
UniProt IDQ29980
Entrez Gene ID4277
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)