Vhf05915 details

Gene vhfRNAi AccessionVhf05915
Gene SymbolCOL11
Gene DescriptionCollectin-11 (Collectin kidney protein 1) (CL-K1)
Gene Name in PaperCOL11
GroupHost Factor
Ensembl Gene IDENST00000236693 ENST00000349077 ENST00000382062 ENST00000402794 ENST00000402922 ENST00000403096 ENST00000404205 ENST00000418971 
UniProt IDQ9BWP8
Entrez Gene ID78989
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)