Vhf05876 details

Gene vhfRNAi AccessionVhf05876
Gene SymbolCHCH7
Gene DescriptionCoiled-coil-helix-coiled-coil-helix domain-containing protein 7
Gene Name in PaperCHCH7
GroupHost Factor
Ensembl Gene IDENST00000303759 ENST00000355315 ENST00000518801 ENST00000519367 ENST00000521524 ENST00000521831 ENST00000523975 
UniProt IDQ9BUK0
Entrez Gene ID79145
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)