RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf05875 |
| Gene Symbol | STK25 | |
| Gene Description | Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1) | |
| Gene Name in Paper | STK25 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000316586 ENST00000401869 ENST00000403346 ENST00000405585 ENST00000405883 ENST00000535007 ENST00000543554 | |
| UniProt ID | O00506 | |
| Entrez Gene ID | 10494 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |