Vhf05868 details

Gene vhfRNAi AccessionVhf05868
Gene SymbolIPKG
Gene DescriptioncAMP-dependent protein kinase inhibitor gamma (PKI-gamma)
Gene Name in PaperIPKG
GroupHost Factor
Ensembl Gene IDENST00000349959 ENST00000372886 ENST00000372889 ENST00000372891 ENST00000372892 ENST00000372894 
UniProt IDQ9Y2B9
Entrez Gene ID11142
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)