RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf05852 |
Gene Symbol | VPS16 | |
Gene Description | Vacuolar protein sorting-associated protein 16 homolog (hVPS16) | |
Gene Name in Paper | VPS16 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000380445 ENST00000380469 | |
UniProt ID | Q9H269 | |
Entrez Gene ID | 64601 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Marburgvirus |
Virus Abbreviation | MARV | |
Taxonomy | View | |
Results | Phenotype | Inhibited infection |
Hits Number* | 173 | |
Confirmed Hits Number | 106 | |
Score | ?4.93 | |
Unit | z-score | |
Methods | Assay Type | cell-based |
BioModel Description | Human 293T embryonic kidney cells and human lung epithelial A549 cells | |
Confirmatory Screen Description | Luciferase | |
Primary Screen Description# | z-scores greater than 2 | |
Note/Comment | Identify host proteins important for entry of Marburg virus | |
References | Pubmed ID | 26596270 |