RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf05850 |
| Gene Symbol | HAVR1 | |
| Gene Description | Hepatitis A virus cellular receptor 1 (HAVcr-1) (Kidney injury molecule 1) (KIM-1) (T-cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T-cell immunoglobulin mucin receptor 1) (TIM) (TIM-1) (T-cell membrane protein 1) | |
| Gene Name in Paper | NA | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000339252 ENST00000523175 | |
| UniProt ID | Q96D42 | |
| Entrez Gene ID | 26762 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Marburgvirus |
| Virus Abbreviation | MARV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited infection |
| Hits Number* | 173 | |
| Confirmed Hits Number | 106 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | Human 293T embryonic kidney cells and human lung epithelial A549 cells | |
| Confirmatory Screen Description | Luciferase | |
| Primary Screen Description# | z-scores greater than 2 | |
| Note/Comment | Identify host proteins important for entry of Marburg virus | |
| References | Pubmed ID | 26596270 |