RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf05432 |
Gene Symbol | MAVS | |
Gene Description | Mitochondrial antiviral-signaling protein | |
Gene Name in Paper | MAVS | |
Group | Restriction Factor | |
Ensembl Gene ID | ENSG00000088888 | |
UniProt ID | Q7Z434 | |
Entrez Gene ID | 57506 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Influenza A virus |
Virus Abbreviation | IAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited infection |
Hits Number* | 1745 | |
Confirmed Hits Number | 616 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | Human bronchial epithelial cells (HBECs) for screening 2146 siRNA duplexes (SMARTpools, Dharmacon, high titer lentiviruses encoding shRNA-targeting genes of interest) | |
Confirmatory Screen Description | Not mentioned | |
Primary Screen Description# | Not mentioned | |
Note/Comment | Inhibited infection (616) | |
References | Pubmed ID | 20064372 |