Vhf05256 details

Gene vhfRNAi AccessionVhf05256
Gene SymbolPOLR3B
Gene DescriptionDNA-directed RNA polymerase III subunit RPC2
Gene Name in PaperPOLR3B
GroupRestriction Factor
Ensembl Gene IDENST00000228347 
UniProt IDQ9NW08
Entrez Gene ID55703
GOView
Host OrganismHomo sapiens
Virus Virus full nameInfluenza A virus
Virus AbbreviationIAV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*1745
Confirmed Hits Number616
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHuman bronchial epithelial cells (HBECs) for screening 2146 siRNA duplexes (SMARTpools, Dharmacon, high titer lentiviruses encoding shRNA-targeting genes of interest)
Confirmatory Screen DescriptionNot mentioned
Primary Screen Description#Not mentioned
Note/CommentInhibited infection (616)
References Pubmed ID20064372
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)