Vhf04946 details

Gene vhfRNAi AccessionVhf04946
Gene SymbolCDK12
Gene DescriptionCyclin-dependent kinase 12
Gene Name in PaperCDK12
GroupRestriction Factor
Ensembl Gene IDENSG00000167258 
UniProt IDQ9NYV4
Entrez Gene ID51755
GOView
Host OrganismHomo sapiens
Virus Virus full nameInfluenza A virus
Virus AbbreviationIAV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*1745
Confirmed Hits Number616
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHuman bronchial epithelial cells (HBECs) for screening 2146 siRNA duplexes (SMARTpools, Dharmacon, high titer lentiviruses encoding shRNA-targeting genes of interest)
Confirmatory Screen DescriptionNot mentioned
Primary Screen Description#Not mentioned
Note/CommentInhibited infection (616)
References Pubmed ID20064372
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)