RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf04542 |
| Gene Symbol | EIF4A3 | |
| Gene Description | Eukaryotic initiation factor 4A-III | |
| Gene Name in Paper | EIF4A3 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000269349 | |
| UniProt ID | P38919 | |
| Entrez Gene ID | 9775 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Influenza A virus |
| Virus Abbreviation | IAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited infection |
| Hits Number* | 287 | |
| Confirmed Hits Number | 168 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | A549 human lung epithelial cells for screening a genome-wide siRNA library consisting of approximately 62,000 siRNAs targeting 17,000 annotated genes and 6,000 predicted genes | |
| Confirmatory Screen Description | Confirmed hits were validated using both influenza A H1N1 virus (A/WSN/33) and swine-origin influenza A/Hamburg/04/2009 (H1N1) virus. | |
| Primary Screen Description# | Not Specified | |
| Note/Comment | Inhibited infection_common(72 common). Primary hits were validated using highly pathogenic avian-origin influenza A virus of the H5N1 subtype (A/Vietnam/1203/2004). | |
| References | Pubmed ID | 20081832 |