RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf04432 |
| Gene Symbol | ACOT2 | |
| Gene Description | Acyl-coenzyme A thioesterase 2, mitochondrial | |
| Gene Name in Paper | ACOT2 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENSG00000119673 | |
| UniProt ID | P49753 | |
| Entrez Gene ID | 10965 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Influenza A virus |
| Virus Abbreviation | IAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited infection |
| Hits Number* | 110 | |
| Confirmed Hits Number | 38 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | Human lung adenocarcinoma epithelial cells (A549) cells for screening the genome-wide TRC shRNA library, consisting of 81,925 shRNAs and targeting to 16,368 human genes | |
| Confirmatory Screen Description | Confirmed hit could show expression in EST analysis or in microarray analysis , i.e. , hit by two unique shRNAs showing at least 40% reduction of viral replication. | |
| Primary Screen Description# | Genes are defined to be hits if at least two unique shRNAs targeted the same gene. | |
| Note/Comment | Inhibited infection(38) | |
| References | Pubmed ID | 24101521 |