Vhf03317 details

Gene vhfRNAi AccessionVhf03317
Gene SymbolSTAG3
Gene DescriptionCohesin subunit SA-3 (SCC3 homolog 3) (Stromal antigen 3) (Stromalin-3)
Gene Name in PaperSTAG3
GroupRestriction Factor
Ensembl Gene IDENST00000317296 ENST00000394018 ENST00000426455 ENST00000620100 
UniProt IDQ9UJ98
Entrez Gene ID10734
GOView
Host OrganismHomo sapiens
Virus Virus full nameHuman immunodeficiency virus 1
Virus AbbreviationHIV-1
TaxonomyView
Results PhenotypeDown regulated
Hits Number*3043
Confirmed Hits Number1083
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionCD4+ T-cell subsets enriched in cells exhibiting Th17 (CCR4+CCR6+), Th1 (CXCR3+CCR6?), Th2 (CCR4+CCR6?), and Th1Th17 (CXCR3+CCR6+)
Confirmatory Screen DescriptionSYBR Green real-time RT-PCR 
Primary Screen Description#Differentially expressed genes based on p value < 0.05 and fold change (FC, cut-off 1.3)
Note/CommentIdentification of novel HIV-1 dependency factors
References Pubmed ID26654242
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)