Vhf03257 details

Gene vhfRNAi AccessionVhf03257
Gene SymbolMPCP
Gene DescriptionPhosphate carrier protein, mitochondrial (Phosphate transport protein) (PTP) (Solute carrier family 25 member 3)
Gene Name in PaperMPCP
GroupRestriction Factor
Ensembl Gene IDENST00000188376 ENST00000228318 ENST00000401722 ENST00000549338 ENST00000551917 ENST00000552981 
UniProt IDQ00325
Entrez Gene ID5250
GOView
Host OrganismHomo sapiens
Virus Virus full nameHuman immunodeficiency virus 1
Virus AbbreviationHIV-1
TaxonomyView
Results PhenotypeDown regulated
Hits Number*3043
Confirmed Hits Number1083
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionCD4+ T-cell subsets enriched in cells exhibiting Th17 (CCR4+CCR6+), Th1 (CXCR3+CCR6?), Th2 (CCR4+CCR6?), and Th1Th17 (CXCR3+CCR6+)
Confirmatory Screen DescriptionSYBR Green real-time RT-PCR 
Primary Screen Description#Differentially expressed genes based on p value < 0.05 and fold change (FC, cut-off 1.3)
Note/CommentIdentification of novel HIV-1 dependency factors
References Pubmed ID26654242
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)