Vhf02973 details

Gene vhfRNAi AccessionVhf02973
Gene SymbolCNDH2
Gene DescriptionCondensin-2 complex subunit H2 (Chromosome-associated protein H2) (hCAP-H2) (Kleisin-beta) (Non-SMC condensin II complex subunit H2)
Gene Name in PaperCNDH2
GroupRestriction Factor
Ensembl Gene IDENST00000299821 ENST00000395698 ENST00000420993 
UniProt IDQ6IBW4
Entrez Gene ID29781
GOView
Host OrganismHomo sapiens
Virus Virus full nameHuman immunodeficiency virus 1
Virus AbbreviationHIV-1
TaxonomyView
Results PhenotypeDown regulated
Hits Number*3043
Confirmed Hits Number1083
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionCD4+ T-cell subsets enriched in cells exhibiting Th17 (CCR4+CCR6+), Th1 (CXCR3+CCR6?), Th2 (CCR4+CCR6?), and Th1Th17 (CXCR3+CCR6+)
Confirmatory Screen DescriptionSYBR Green real-time RT-PCR 
Primary Screen Description#Differentially expressed genes based on p value < 0.05 and fold change (FC, cut-off 1.3)
Note/CommentIdentification of novel HIV-1 dependency factors
References Pubmed ID26654242
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)