RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf02897 |
| Gene Symbol | MBOA7 | |
| Gene Description | Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (1-acylglycerophosphatidylinositol O-acyltransferase) (EC 2.3.1.n4) (Bladder and breast carcinoma-overexpressed gene 1 protein) (Leukocyte receptor cluster member 4) (Lysophosphatidylinositol acyltransferase) (LPIAT) (Lyso-PI acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) (h-mboa-7) | |
| Gene Name in Paper | MBOA7 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000245615 ENST00000338624 ENST00000391754 ENST00000431666 ENST00000610862 ENST00000611239 ENST00000611602 ENST00000612053 ENST00000612567 ENST00000613506 ENST00000613746 ENST00000614279 ENST00000615282 ENST00000615453 ENST00000617012 ENST00000617656 ENST00000617772 ENST00000618378 ENST00000618826 ENST00000618899 ENST00000619670 ENST00000619745 ENST00000619842 ENST00000619855 ENST00000620311 ENST00000620371 ENST00000620636 ENST00000621146 ENST00000621455 ENST00000621612 ENST00000621875 | |
| UniProt ID | Q96N66 | |
| Entrez Gene ID | 79143 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Human immunodeficiency virus 1 |
| Virus Abbreviation | HIV-1 | |
| Taxonomy | View | |
| Results | Phenotype | Down regulated |
| Hits Number* | 3043 | |
| Confirmed Hits Number | 1083 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | CD4+ T-cell subsets enriched in cells exhibiting Th17 (CCR4+CCR6+), Th1 (CXCR3+CCR6?), Th2 (CCR4+CCR6?), and Th1Th17 (CXCR3+CCR6+) | |
| Confirmatory Screen Description | SYBR Green real-time RT-PCR | |
| Primary Screen Description# | Differentially expressed genes based on p value < 0.05 and fold change (FC, cut-off 1.3) | |
| Note/Comment | Identification of novel HIV-1 dependency factors | |
| References | Pubmed ID | 26654242 |