RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf02845 |
| Gene Symbol | KI2L4 | |
| Gene Description | Killer cell immunoglobulin-like receptor 2DL4 (CD158 antigen-like family member D) (G9P) (Killer cell inhibitory receptor 103AS) (KIR-103AS) (MHC class I NK cell receptor KIR103AS) (CD antigen CD158d) | |
| Gene Name in Paper | KI2L4 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000345540 ENST00000357494 ENST00000396293 ENST00000611022 ENST00000612573 ENST00000612660 ENST00000613053 ENST00000614653 ENST00000614680 ENST00000615232 ENST00000615243 ENST00000615970 ENST00000616354 ENST00000616384 ENST00000618297 ENST00000618358 ENST00000618567 ENST00000619637 ENST00000619848 ENST00000620484 ENST00000620486 ENST00000621182 | |
| UniProt ID | Q99706 | |
| Entrez Gene ID | 3805 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Human immunodeficiency virus 1 |
| Virus Abbreviation | HIV-1 | |
| Taxonomy | View | |
| Results | Phenotype | Down regulated |
| Hits Number* | 3043 | |
| Confirmed Hits Number | 1083 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | CD4+ T-cell subsets enriched in cells exhibiting Th17 (CCR4+CCR6+), Th1 (CXCR3+CCR6?), Th2 (CCR4+CCR6?), and Th1Th17 (CXCR3+CCR6+) | |
| Confirmatory Screen Description | SYBR Green real-time RT-PCR | |
| Primary Screen Description# | Differentially expressed genes based on p value < 0.05 and fold change (FC, cut-off 1.3) | |
| Note/Comment | Identification of novel HIV-1 dependency factors | |
| References | Pubmed ID | 26654242 |