Vhf02456 details

Gene vhfRNAi AccessionVhf02456
Gene SymbolCOPRS
Gene DescriptionCoordinator of PRMT5 and differentiation stimulator (Cooperator of PRMT5) (Protein TTP1)
Gene Name in PaperCOPRS
GroupRestriction Factor
Ensembl Gene IDENST00000302362 
UniProt IDQ9NQ92
Entrez Gene ID55352
GOView
Host OrganismHomo sapiens
Virus Virus full nameHuman immunodeficiency virus 1
Virus AbbreviationHIV-1
TaxonomyView
Results PhenotypeDown regulated
Hits Number*3043
Confirmed Hits Number1083
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionCD4+ T-cell subsets enriched in cells exhibiting Th17 (CCR4+CCR6+), Th1 (CXCR3+CCR6?), Th2 (CCR4+CCR6?), and Th1Th17 (CXCR3+CCR6+)
Confirmatory Screen DescriptionSYBR Green real-time RT-PCR 
Primary Screen Description#Differentially expressed genes based on p value < 0.05 and fold change (FC, cut-off 1.3)
Note/CommentIdentification of novel HIV-1 dependency factors
References Pubmed ID26654242
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)