Vhf02120 details

Gene vhfRNAi AccessionVhf02120
Gene SymbolFA53B
Gene DescriptionProtein FAM53B
Gene Name in PaperFA53B
GroupHost Factor
Ensembl Gene IDENST00000280780 ENST00000337318 ENST00000392754 
UniProt IDQ14153
Entrez Gene ID9679
GOView
Host OrganismHomo sapiens
Virus Virus full nameHuman immunodeficiency virus 1
Virus AbbreviationHIV-1
TaxonomyView
Results PhenotypeUp regulated
Hits Number*3043
Confirmed Hits Number1083
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionCD4+ T-cell subsets enriched in cells exhibiting Th17 (CCR4+CCR6+), Th1 (CXCR3+CCR6?), Th2 (CCR4+CCR6?), and Th1Th17 (CXCR3+CCR6+)
Confirmatory Screen DescriptionSYBR Green real-time RT-PCR 
Primary Screen Description#Differentially expressed genes based on p value < 0.05 and fold change (FC, cut-off 1.3)
Note/CommentIdentification of novel HIV-1 dependency factors
References Pubmed ID26654242
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)