Vhf02027 details

Gene vhfRNAi AccessionVhf02027
Gene SymbolDP13B
Gene DescriptionDCC-interacting protein 13-beta (Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2)
Gene Name in PaperDP13B
GroupHost Factor
Ensembl Gene IDENST00000258530 ENST00000539978 ENST00000551662 
UniProt IDQ8NEU8
Entrez Gene ID55198
GOView
Host OrganismHomo sapiens
Virus Virus full nameHuman immunodeficiency virus 1
Virus AbbreviationHIV-1
TaxonomyView
Results PhenotypeUp regulated
Hits Number*3043
Confirmed Hits Number1083
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionCD4+ T-cell subsets enriched in cells exhibiting Th17 (CCR4+CCR6+), Th1 (CXCR3+CCR6?), Th2 (CCR4+CCR6?), and Th1Th17 (CXCR3+CCR6+)
Confirmatory Screen DescriptionSYBR Green real-time RT-PCR 
Primary Screen Description#Differentially expressed genes based on p value < 0.05 and fold change (FC, cut-off 1.3)
Note/CommentIdentification of novel HIV-1 dependency factors
References Pubmed ID26654242
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)