RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf02015 |
Gene Symbol | ABLM1 | |
Gene Description | Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin) | |
Gene Name in Paper | ABLM1 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000277895 ENST00000369253 ENST00000369256 ENST00000392952 ENST00000392955 | |
UniProt ID | O14639 | |
Entrez Gene ID | 3983 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Human immunodeficiency virus 1 |
Virus Abbreviation | HIV-1 | |
Taxonomy | View | |
Results | Phenotype | Up regulated |
Hits Number* | 3043 | |
Confirmed Hits Number | 1083 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | CD4+ T-cell subsets enriched in cells exhibiting Th17 (CCR4+CCR6+), Th1 (CXCR3+CCR6?), Th2 (CCR4+CCR6?), and Th1Th17 (CXCR3+CCR6+) | |
Confirmatory Screen Description | SYBR Green real-time RT-PCR | |
Primary Screen Description# | Differentially expressed genes based on p value < 0.05 and fold change (FC, cut-off 1.3) | |
Note/Comment | Identification of novel HIV-1 dependency factors | |
References | Pubmed ID | 26654242 |