Vhf01562 details

Gene vhfRNAi AccessionVhf01562
Gene SymbolMAP2K7
Gene DescriptionDual specificity mitogen-activated protein kinase kinase 7
Gene Name in PaperMKK7
GroupRestriction Factor
Ensembl Gene IDENSG00000076984 
UniProt IDO14733
Entrez Gene ID5609
GOView
Host OrganismHomo sapiens
Virus Virus full nameHepatitis C virus
Virus AbbreviationHCV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*>200
Confirmed Hits Number8
Score80 ± 9
UnitRNA inhibition
Methods Assay Type Cell-based
BioModel DescriptionHuh7 cells derived EN5-3 cells for screening the SMARTpool siRNA library of 4,000 human genes
Confirmatory Screen Description Inhibition of HCV RNA replication and MTT assay for cell toxicity
Primary Screen Description# Inhibition of HCV RNA replication and MTT assay for cell toxicity
Note/CommentInhibited infection(8)
References Pubmed ID17518369
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)