RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01562 |
| Gene Symbol | MAP2K7 | |
| Gene Description | Dual specificity mitogen-activated protein kinase kinase 7 | |
| Gene Name in Paper | MKK7 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENSG00000076984 | |
| UniProt ID | O14733 | |
| Entrez Gene ID | 5609 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Hepatitis C virus |
| Virus Abbreviation | HCV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited infection |
| Hits Number* | >200 | |
| Confirmed Hits Number | 8 | |
| Score | 80 ± 9 | |
| Unit | RNA inhibition | |
| Methods | Assay Type | Cell-based |
| BioModel Description | Huh7 cells derived EN5-3 cells for screening the SMARTpool siRNA library of 4,000 human genes | |
| Confirmatory Screen Description | Inhibition of HCV RNA replication and MTT assay for cell toxicity | |
| Primary Screen Description# | Inhibition of HCV RNA replication and MTT assay for cell toxicity | |
| Note/Comment | Inhibited infection(8) | |
| References | Pubmed ID | 17518369 |