Vhf01559 details

Gene vhfRNAi AccessionVhf01559
Gene SymbolTBXA2R
Gene DescriptionThromboxane A2 receptor
Gene Name in PaperTBXA2R
GroupRestriction Factor
Ensembl Gene IDENST00000375190 
UniProt IDP21731
Entrez Gene ID6915
GOView
Host OrganismHomo sapiens
Virus Virus full nameHepatitis C virus
Virus AbbreviationHCV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*>200
Confirmed Hits Number8
Score91 ± 18
UnitRNA inhibition
Methods Assay Type Cell-based
BioModel DescriptionHuh7 cells derived EN5-3 cells for screening the SMARTpool siRNA library of 4,000 human genes
Confirmatory Screen Description Inhibition of HCV RNA replication and MTT assay for cell toxicity
Primary Screen Description# Inhibition of HCV RNA replication and MTT assay for cell toxicity
Note/CommentInhibited infection(8)
References Pubmed ID17518369
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)