RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01466 |
Gene Symbol | FOLR1 | |
Gene Description | Folate receptor alpha (FR-alpha) (Adult folate-binding protein) (FBP) (Folate receptor 1) (Folate receptor, adult) (KB cells FBP) (Ovarian tumor-associated antigen MOv18) | |
Gene Name in Paper | FOLR1 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000312293 ENST00000393676 ENST00000393679 ENST00000393681 | |
UniProt ID | P15328 | |
Entrez Gene ID | 2348 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Avian influenza virus |
Virus Abbreviation | AIV | |
Taxonomy | View | |
Results | Phenotype | Inhibited infection |
Hits Number* | 109 | |
Confirmed Hits Number | 42 | |
Score | 0.46 | |
Unit | siRNA score | |
Methods | Assay Type | cell-based |
BioModel Description | Human 293T embryonic kidney cells and human lung epithelial A549 cells | |
Confirmatory Screen Description | Luciferase | |
Primary Screen Description# | z-scores greater than 2 | |
Note/Comment | Identify host proteins important for H5N1 influenza virus | |
References | Pubmed ID | 26596270 |