Vhf01457 details

Gene vhfRNAi AccessionVhf01457
Gene SymbolLCE1E
Gene DescriptionLate cornified envelope protein 1E (Late envelope protein 5)
Gene Name in PaperLCE1E
GroupHost Factor
Ensembl Gene IDENST00000368770  ENST00000368771  
UniProt IDQ5T753
Entrez Gene ID353135
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeIncreased transduction
Hits Number*1483
Confirmed Hits Number515
Score?9.8
UnitFold change
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)