RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01455 |
| Gene Symbol | PARP8 | |
| Gene Description | Poly [ADP-ribose] polymerase 8 (PARP-8) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 16) (ARTD16) | |
| Gene Name in Paper | FLJ21308 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000281631 ENST00000505697 ENST00000514067 | |
| UniProt ID | Q8N3A8 | |
| Entrez Gene ID | 79668 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | ?9.4 | |
| Unit | Fold change | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |