RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01451 |
Gene Symbol | CTSR3 | |
Gene Description | Cation channel sperm-associated protein 3 (CatSper3) (Ca(v)-like protein) (One-repeat calcium channel-like protein) | |
Gene Name in Paper | CATSPER3 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000282611 | |
UniProt ID | Q86XQ3 | |
Entrez Gene ID | 347732 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | ?8.9 | |
Unit | Fold change | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |