RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01448 |
Gene Symbol | ATNG | |
Gene Description | Sodium/potassium-transporting ATPase subunit gamma (Na(+)/K(+) ATPase subunit gamma) (FXYD domain-containing ion transport regulator 2) (Sodium pump gamma chain) | |
Gene Name in Paper | FXYD2 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000260287 ENST00000292079 ENST00000528014 ENST00000532119 | |
UniProt ID | P54710 | |
Entrez Gene ID | 486 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |