Vhf01386 details

Gene vhfRNAi AccessionVhf01386
Gene SymbolANK1
Gene DescriptionAnkyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin)
Gene Name in PaperANK1
GroupHost Factor
Ensembl Gene IDENST00000265709  ENST00000289734  ENST00000314214  ENST00000347528  ENST00000348036  ENST00000522543  
UniProt IDP16157
Entrez Gene ID286
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeIncreased transduction
Hits Number*1483
Confirmed Hits Number515
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)