RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01385 |
Gene Symbol | CTL4 | |
Gene Description | Choline transporter-like protein 4 (Solute carrier family 44 member 4) | |
Gene Name in Paper | C6ORF29 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000229729 ENST00000375562 ENST00000383379 ENST00000415517 ENST00000417894 ENST00000425238 ENST00000442152 ENST00000453831 ENST00000544672 ENST00000546461 ENST00000547493 ENST00000547684 ENST00000548188 ENST00000549663 ENST00000549677 ENST00000550401 ENST00000551168 ENST00000553121 | |
UniProt ID | Q53GD3 | |
Entrez Gene ID | 80736 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |