RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01374 |
| Gene Symbol | NFKB1 | |
| Gene Description | Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit] | |
| Gene Name in Paper | NFKB1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000226574 ENST00000394820 ENST00000505458 ENST00000600343 | |
| UniProt ID | P19838 | |
| Entrez Gene ID | 4790 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |