RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01365 |
| Gene Symbol | VSTM1 | |
| Gene Description | V-set and transmembrane domain-containing protein 1 (Signal inhibitory receptor on leukocytes-1) (SIRL-1) | |
| Gene Name in Paper | UNQ3033 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000338372 ENST00000376626 ENST00000447872 ENST00000610629 ENST00000610794 ENST00000610804 ENST00000611293 ENST00000612105 ENST00000612436 ENST00000612864 ENST00000613042 ENST00000615235 ENST00000615508 ENST00000616717 ENST00000617115 ENST00000617281 ENST00000617776 ENST00000617862 ENST00000619024 ENST00000619921 ENST00000620474 ENST00000622762 | |
| UniProt ID | Q6UX27 | |
| Entrez Gene ID | 284415 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |