RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01316 |
Gene Symbol | ARP21 | |
Gene Description | cAMP-regulated phosphoprotein 21 (ARPP-21) (Thymocyte cAMP-regulated phosphoprotein) | |
Gene Name in Paper | ARPP-21 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000187397 ENST00000396481 ENST00000396482 ENST00000412048 ENST00000417925 ENST00000427542 ENST00000428373 ENST00000432682 ENST00000436702 ENST00000438071 ENST00000441454 ENST00000444190 ENST00000474696 | |
UniProt ID | Q9UBL0 | |
Entrez Gene ID | 10777 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |