RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01304 |
Gene Symbol | PSG5 | |
Gene Description | Pregnancy-specific beta-1-glycoprotein 5 (PS-beta-G-5) (PSBG-5) (Pregnancy-specific glycoprotein 5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3) | |
Gene Name in Paper | PSG5 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000342951 ENST00000366175 ENST00000407356 | |
UniProt ID | Q15238 | |
Entrez Gene ID | 5673 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |