RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01284 |
Gene Symbol | ACOT9 | |
Gene Description | Acyl-coenzyme A thioesterase 9, mitochondrial (Acyl-CoA thioesterase 9) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 9) | |
Gene Name in Paper | ACATE2 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000336430 ENST00000379295 ENST00000379303 | |
UniProt ID | Q9Y305 | |
Entrez Gene ID | 23597 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |