RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01264 |
Gene Symbol | DHRS7 | |
Gene Description | Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) | |
Gene Name in Paper | DHRS7 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000216500 ENST00000536410 ENST00000557185 | |
UniProt ID | Q9Y394 | |
Entrez Gene ID | 51635 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |