RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01254 |
| Gene Symbol | FAHD1 | |
| Gene Description | Acylpyruvase FAHD1, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1) (FAH domain-containing protein 1) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.3) (YisK-like protein) | |
| Gene Name in Paper | DKFZP566J2046 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000382666 ENST00000382668 ENST00000427358 ENST00000615972 | |
| UniProt ID | Q6P587 | |
| Entrez Gene ID | 81889 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |