RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01251 |
Gene Symbol | H31 | |
Gene Description | Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l) | |
Gene Name in Paper | HIST1H3J | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000356476 ENST00000359303 ENST00000369163 ENST00000612966 ENST00000613854 ENST00000614378 ENST00000614911 ENST00000616365 ENST00000618052 ENST00000621411 ENST00000634733 | |
UniProt ID | P68431 | |
Entrez Gene ID | 8356 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |