RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01246 |
| Gene Symbol | LFG1 | |
| Gene Description | Protein lifeguard 1 (Glutamate [NMDA] receptor-associated protein 1) (NMDA receptor glutamate-binding subunit) (Putative MAPK-activating protein PM02) (Transmembrane BAX inhibitor motif-containing protein 3) | |
| Gene Name in Paper | GRINA | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000313269 ENST00000395068 | |
| UniProt ID | Q7Z429 | |
| Entrez Gene ID | 2907 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |