RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01241 |
| Gene Symbol | MSH5 | |
| Gene Description | MutS protein homolog 5 (hMSH5) | |
| Gene Name in Paper | MSH5 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000375703 ENST00000375740 ENST00000375750 ENST00000375755 ENST00000412070 ENST00000416549 ENST00000419269 ENST00000420731 ENST00000427735 ENST00000435700 ENST00000436091 ENST00000436192 ENST00000441395 ENST00000441401 ENST00000448617 ENST00000456839 ENST00000457742 | |
| UniProt ID | O43196 | |
| Entrez Gene ID | 4439 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |