Vhf01205 details

Gene vhfRNAi AccessionVhf01205
Gene SymbolNEUR1
Gene DescriptionSialidase-1 (EC 3.2.1.18) (Acetylneuraminyl hydrolase) (G9 sialidase) (Lysosomal sialidase) (N-acetyl-alpha-neuraminidase 1)
Gene Name in PaperNEU1
GroupHost Factor
Ensembl Gene IDENST00000229725  ENST00000375631  ENST00000411774  ENST00000422978  ENST00000423382  ENST00000434496  ENST00000437432  ENST00000439648  
UniProt IDQ99519
Entrez Gene ID4758
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeIncreased transduction
Hits Number*1483
Confirmed Hits Number515
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)