RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01198 |
Gene Symbol | AFG32 | |
Gene Description | AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein) | |
Gene Name in Paper | AFG3L2 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000269143 | |
UniProt ID | Q9Y4W6 | |
Entrez Gene ID | 10939 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |