Vhf01188 details

Gene vhfRNAi AccessionVhf01188
Gene SymbolDDX4
Gene DescriptionProbable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog)
Gene Name in PaperDDX4
GroupHost Factor
Ensembl Gene IDENST00000353507  ENST00000354991  ENST00000505374  ENST00000511853  ENST00000514278  
UniProt IDQ9NQI0
Entrez Gene ID54514
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeIncreased transduction
Hits Number*1483
Confirmed Hits Number515
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)