Vhf01173 details

Gene vhfRNAi AccessionVhf01173
Gene SymbolMFF
Gene DescriptionMitochondrial fission factor
Gene Name in PaperGL004
GroupHost Factor
Ensembl Gene IDENST00000304593  ENST00000337110  ENST00000349901  ENST00000353339  ENST00000354503  ENST00000409565  ENST00000409616  
UniProt IDQ9GZY8
Entrez Gene ID56947
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeIncreased transduction
Hits Number*1483
Confirmed Hits Number515
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)