RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf01167 |
Gene Symbol | DPP9 | |
Gene Description | Dipeptidyl peptidase 9 (DP9) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2) (Dipeptidyl peptidase IX) (DPP IX) (Dipeptidyl peptidase-like protein 9) (DPLP9) | |
Gene Name in Paper | DPP9 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000262960 ENST00000594671 ENST00000598800 | |
UniProt ID | Q86TI2 | |
Entrez Gene ID | 91039 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |