RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01151 |
| Gene Symbol | NDRG4 | |
| Gene Description | Protein NDRG4 (Brain development-related molecule 1) (N-myc downstream-regulated gene 4 protein) (Vascular smooth muscle cell-associated protein 8) (SMAP-8) | |
| Gene Name in Paper | NDRG4 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000258187 ENST00000356752 ENST00000394279 ENST00000394282 ENST00000563799 ENST00000566192 ENST00000568640 ENST00000570248 | |
| UniProt ID | Q9ULP0 | |
| Entrez Gene ID | 65009 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |