RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01094 |
| Gene Symbol | MED16 | |
| Gene Description | Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) (Thyroid hormone receptor-associated protein 5) (Thyroid hormone receptor-associated protein complex 95 kDa component) (Trap95) (Vitamin D3 receptor-interacting protein complex 92 kDa component) (DRIP92) | |
| Gene Name in Paper | THRAP5 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000312090 ENST00000325464 ENST00000395808 ENST00000589119 | |
| UniProt ID | Q9Y2X0 | |
| Entrez Gene ID | 10025 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |