Vhf01087 details

Gene vhfRNAi AccessionVhf01087
Gene SymbolMTO1
Gene DescriptionProtein MTO1 homolog, mitochondrial
Gene Name in PaperMTO1
GroupHost Factor
Ensembl Gene IDENST00000370300  ENST00000370305  ENST00000415954  ENST00000498286  
UniProt IDQ9Y2Z2
Entrez Gene ID25821
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeIncreased transduction
Hits Number*1483
Confirmed Hits Number515
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)