RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01052 |
| Gene Symbol | AT2C1 | |
| Gene Description | Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 3.6.3.8) (ATP-dependent Ca(2+) pump PMR1) | |
| Gene Name in Paper | ATP2C1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000328560 ENST00000359644 ENST00000422190 ENST00000428331 ENST00000504381 ENST00000504948 ENST00000507488 ENST00000508532 ENST00000510168 ENST00000513801 ENST00000533801 | |
| UniProt ID | P98194 | |
| Entrez Gene ID | 27032 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |